
Textbook of Cytogenetics. 1972. W. V. Brown, Chapt. 4 and 6.
MITOSIS:
Telophase -- "resting stage" -- actually metabolically can be very active, DNA synthesis for chromatids is going on. 2C to 4C
Prophase -- chromosomes become visible and contract, chromosome are two chromatids, but the chromosomes do not pair. Nucleolus and nuclear membrane disappear. 4C
Metaphase -- doubled chromosomes at the equational plate. Chromatids separate to form two daughter chromosomes, spindle formation. 4C
Anaphase -- daughter chromosomes move to the poles, cytokinesis (cell division). 4C back to 2C
MEIOSIS
Cell cycle: S1, G1, S2, G2 occur before prophase 1. S is for DNA synthesis, G is for resting stage between DNA synthesis.
Egg mother cell (megasporocyte) and pollen mother cell (microsporocyte) contain 2 chromosomes of each kind (2N).
Prophase 1: Can be broken down into many distinct stages (leptotene, zygotene, pachytene, diplotene, diakinesis). Nuclear membrane and nucleolus disappear. Chromosomes become visible, homologous pair, formation of chromatids, crossing-over. 2C to 4C
| Metaphase 1: | Chromosomes at equational plate. 4C |
| Anaphase 1: | Chromosomes (not chromatids) moving poleward. 4C |
| Telophase 1: | Nuclear membrane restored. Each nucleus contains ½ the number of chromosomes. 4C to 2C Then follows a mitotic like division of prophase 2 (2C), metaphase 2(2C), anaphase 2 (2C), telophase 2 (2C to 1C due to formation of cell wall) to tetrad formation. This the formation of spores. |
Key features of meiosis:
1. Egg mother cell (megasporocyte) and pollen mother cell (microsporocyte) contain 2 chromosomes of each kind.
2. In prophase 1, members of a pair usually synapse and crossing-over usually occurs.
3. At anaphase 1 and telophase 1 members of a pair go to opposite poles and into daughter cells now with reduced chromosome number (N).
4. Meiosis includes a mitotic-like division to give 4 cells with "n" chromosome number. These cells are called spores.
5. Recombination and segregation of genetic materials occur.