Degrees

• B.S. in Biochemistry University of Illinois Urbana-Champaign
• Ph.D. in Bioche mistry University of Iowa

Research Interests

Research interests are in the area of agricultural biotechnology, and more specifically in the genetic modification of plants to improve yield, sustainability, environment with an emphasis on drought tolerance. Continued interest in the biochemical study of plant peroxidases with regard to their function and role in plant growth, development, and defense strategies.

Selected Publications

• Dowd, PF and Lagrimini LM (2006). Examination of the biological effects of high anionic peroxidase production in tobacco plants grown under field conditions. I. Insect pest damage. Transgenic Research 15(2):197-204.
   
• Hushpulian DM, Savitski PA, Rojkova AM, Chubar TA, Fechina VA, Sakharov IY, Lagrimini LM, Tishkov VI, Gazaryan IG. (2003). Expression and refolding of tobacco anionic peroxidase from E. coli inclusion bodies. Biochemistry (Mosc)68(11):1189-94.
   
• Jansen MA, van den Noort RE, Tan MY, Prinsen E, Lagrimini LM, Thorneley RN. (2001). Phenol-oxidizing peroxidases contribute to the protection of plants from ultraviolet radiation stress. Plant Physiol. 126(3):1012-23.
   
• Savitsky PA, Gazaryan IG, Tishkov VI, Lagrimini LM, Ruzgas T, Gorton L. (1999). Oxidation of indole-3-acetic acid by dioxygen catalysed by plant peroxidases: specificity for the enzyme structure. Biochem J. 340:579-83.
   
• Dowd, L. M. and Lagrimini, L. M. (1998). Differential leaf resistance to insects of transgenic sweetgum (Liquidamber styraciflua) expressing tobacco anionic peroxidase. Cell. Mol. Life Sci. 54:712-720.
   
• Gazaryan, I. G., Lagrimini, L. M., Mellon, F. A., Naldrett, M. J., Ashby, G. A. and Thorneley, R. N. F. (1998). Identification of skatole hydroperoxide and its role in the peroxidase catalyzed oxidation of indole-3-acetic acid by dioxygen. Biochem. J. 333:323-332.
   
• Klotz, K. L., Liu, T.-T. Y., Liu, L. and Lagrimini, L. M. (1998). Expression of the tobacco anionic peroxidase gene is tissue-specific and developmentally regulated. Plant Mol. Biol. 36:509-520.
   
• Lagrimini, L. M., Gingas, V., and Finger, F, Rothstein, S. and Liu, T. Y. (1997). Characterization of antisense transformed plants deficient in the tobacco anionic peroxidase. Plant Physiol. 114: 1187-1196.
   
• Lagrimini, L. M., Joly, R. J., Dunlap, J. R. and Liu, T-T. Y. (1997). The consequence of peroxidase overexpression in transgenic plants on root growth and development. Plant Mol. Biol. 33:887-895.
   
• Klotz, K. L. and Lagrimini, L. M. (1996). Characterization of the expression of the tobacco anionic peroxidase gene. Plant Mol. Biol.31:561-573.
   
• Gazaryan, I. G. and Lagrimini, L. M. (1996) Tobacco anionic peroxidase overexpressed in transgenic plants. II. Aerobic oxidation of indole-3-acetic acid. Phytochem. 42: 1271-1278.
   
• Gazaryan, I. G. and Lagrimini, L. M. (1996) Tobacco anionic peroxidase overexpressed in transgenic plants. I. Purification and unusual kinetic properties. Phytochem. 41: 1029-1034.
   
• Lagrimini, L. M., Rubihayo, P., Klotz, K., Vaughn, J., Berry, S. and Finer, J. M. (1992). Expres­sion of a tobacco peroxidase gene in transformed tomato plants. J. Am. Soc. Hort. Sci. 117:1012-1016.
   
• Lagrimini, L. M. (1991). Wound-induced deposition of polyphenols in transgenic plants overexpressing peroxidase. Plant Physiol. 96:577-583.
   
• Lagrimini, L. M., Bradford, S. and Rothstein, S. (1990). Peroxidase-induced wilting in transgenic tobacco plants. The Plant Cell 2:7-18.
   
• Lagrimini, L. M., Burkhart, W. A., Moyer, M. B. and Rothstein, S. (1987). Molecular cloning of complementary DNA encoding the lignin-forming peroxidase from tobacco: Molecular analysis and tissue specific expression. Proc. Natl. Acad. Sci. USA 84:7542-7546.