Website:·Plant Root Hair Cell Laboratory
Area of Expertise: Plant Physiology, Weed, and Production Systems
B.S., CELLULAR BIOLOGY AND PHYSIOLOGY, PARIS 7 DENIS DIDEROT UNIVERSITY, FRANCE, 1999
M.S., MOLECULAR AND CELLULAR PLANT PHYSIOLOGY, PARIS 6 PIERRE AND MARIE CURIE UNIVERSITY, FRANCE, 2000
PHD., MOLECULAR AND CELLULAR PLANT PHYSIOLOGY, PARIS SUD-ORSAY UNIVERSITY, FRANCE, 2004
Area of Focus
- Plant root response to biotic and abiotic stresses
- Plant single cell biology
- Comparative genomics
My long term objective is to understand the molecular mechanisms controlling the transcriptional response of agricultural crops to various environmental stresses. Specifically, my lab is working on revealing with great accuracy the influence of the epigenome and binding of transcription factors on crop gene expression in response to biotic and abiotic stresses. To generate unambiguous transcriptomic, epigenomic and functional genomic data sets, my research focuses on plant single cell and single cell-type models such as the root hair cell (RH), a single plant cell type specialized in water and nutrient uptakes. The focus on one single plant cell type represents a unique and integrative systems biology approach to understand then enhance plant response to various environmental stresses including plant response to abiotic stresses and plant-microbe interactions (i.e., legume RH infection by rhizobia). In addition, to develop a more fundamental knowledge of the RH, my lab is also characterizing the evolution of the molecular mechanisms controlling the unique biological properties of the plant RHs (e.g., polar elongation, water and nutrient uptakes). Ultimately, a better understanding of the molecular mechanisms controlling RH development and the adaptation of the RH to environmental stresses will help to enhance RH biology to mitigate climate change, to enhance plant response to environmental stresses and to maximize crop yields.
Major Project Activities
- Exploring the transcriptional regulatory networks controlling the early stages of legume nodulation
- Characterization of the transcriptomic and epigenomic responses of soybean and sorghum root hairs to various environmental stresses
- Comparative-, functional-, and epi-genomics of legumes and nodule formation
- Genomics of energy sorghum’s water use efficiency/drought resilience
- Unraveling the transcriptional regulation controlling root hair cell elongation
- Libault M, Pingault L, Zogli P, and Schiefelbein J, (2017) Plant Systems Biology at the Single-Cell Level. Trends in Plant Science
- Qiao Z, Pingault L, Zogli P, Langevin M, Rech N, Farmer A, and Libault M, (2017) Comprehensive analysis of the divergence and the conservation of the expression of plant genes: insights at the level of one single plant cell type, the root hair cell. Plant Molecular Biology. 94(6):641-655.
- Qiao Z, Brechenmacher L, Smith B, Strout GW, Mangin W, Taylor T, Russell SD, Stacey G, and Libault M, (2017) The GmFWL1 (FW2-2-like) nodulation gene encodes a plasma membrane microdomain-associated protein. Plant, Cell & Environment. 40:1442-1455.
- Qiao Z, Pingault L, Nourbakhsh-Rey M, and Libault M, (2016) Comprehensive comparative genomic and transcriptomic analyses of the legume genes controlling the nodulation process. Frontiers in Plant Science. 7:34.
- Kim KD, El Baidouri M, Abernathy B, Iwata-Otsubo A, Chavarro C, Gonzales M, Libault M, Grimwood J, and Jackson SA, (2015). A Comparative Epigenomic Analysis of Polyploidy-Derived Genes in Soybean and Common Bean. Plant Physiology. 2015 Aug;168(4):1433-47
- Qiao Z, and Libault M, (2013) Unleashing the potential of the root hair cell as a single plant cell type model in root systems biology. Frontiers in Plant Science. 4:484.
- Libault M, Brechenmacher L, Cheng J, Xu D, and Stacey G. (2010) Root hair systems biology. Trends in Plant Science. 11: 641-50.
- Libault M, Farmer A, Joshi T, Takahashi K, Langley RJ, Levi FD, He J, Xu D, May GD, and Stacey G. (2010) An integrated transcriptome atlas of the crop model Glycine max and its use in comparative analyses in plants. The Plant Journal. 63(1):86-99.
- Libault M, Zhang XC, Govindarajulu M, Ong YT, Brechenmacher L, Berg H, Hurley-Sommer A, Qiu J, Taylor CG, and Stacey G. (2010) A member of the highly conserved FWL (tomato FW2.2-like) gene family is essential for soybean nodule organogenesis. The Plant Journal. 62(5):852-64.
- Libault M, Farmer A, Brechenmacher L, Drnevich J, Langley RJ, Bilgin DD, Radman O, Neece DJ, Clough SJ, May GD, and Stacey G. (2010) Complete transcriptome of soybean root hair cell, a single cell model, and its alteration in response to Bradyrhizobium japonicum infection. Plant Physiology. 152(2):541-52. Plant Systems Biology Special Issue 2010.