ASCI 832 – Genome Analysis

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Instructor(s): Daniel C. Ciobanu

Number of Credit Hours: 3

Cross-listings:  ASCI 432

Prerequisites: PLAS 215 and BIOC 401 or equivalent

Description: Theoretical and practical aspects of: structure and function of eukaryotic genomes; genome sequencing and assembling, polymorphism and isoform detection and genotyping; gene and genome annotation; strategies used to identify genetic variants responsible for phenotypic differences; and personalized genomics, social and ethical aspects associated with genomic information.

Learning Outcomes/Course Objectives

  1. Understand principles of inheritance at molecular, cellular, and organismal level.
  2. Analyze and understand data generated by variety of methods for genetic testing, gene expression profile and sequencing.
  3. Demonstrate proficiency in the use of genetic, functional and phenotypic databases, bioinformatics and genomics tools to dissect and understand the genetic sources of high-order phenotypic and molecular variation.